megaloblastic anaemia
Definition
- Noun:
- A type of anemia: Megaloblastic anaemia is a blood disorder characterized by the presence of many large, immature, and dysfunctional red blood cells (called megaloblasts) in the bone marrow. This condition is often associated with a deficiency in vitamin B12 or folate, which are essential for proper red blood cell formation.
Usage Examples
- Noun:
- The patient's fatigue and weakness were diagnosed as symptoms of megaloblastic anaemia.
- A blood test revealed megaloblastic anaemia caused by a severe vitamin B12 deficiency.
Advanced Usage
- Clinical Context: The term is primarily used in medical and clinical settings to describe a specific hematological diagnosis.
- The hematologist specialized in treating cases of megaloblastic anaemia.
Variants and Related Words
- Megaloblastic anemia (noun): An alternative spelling, primarily used in American English.
- Megaloblast (noun): The large, immature red blood cell precursor that characterizes this condition.
- Pernicious anemia (noun): A specific, autoimmune form of megaloblastic anaemia caused by an inability to absorb vitamin B12.
Synonyms
- Macrocytic anemia: A broader term for anemias featuring enlarged red blood cells, which includes megaloblastic anaemia as a primary type.
Related Phrases
- Vitamin B12 deficiency anaemia: A common cause of megaloblastic anaemia.
- Folate deficiency anaemia: Another common cause of megaloblastic anaemia.
Noun
-
anemia characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrow; associated with pernicious anemia
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